Dr. Pat Whitworth on the Importance of the Luminal Subtype in Breast Cancer
March 3rd 2016Whitworth says that while it is generally perceived that the ER-positive/HER2-negative breast cancer patient population is the luminal subtype, 1 of every 5 of those patients would actually considered basal subtype.
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Dr. Harry Bear on Translating Pathological Complete Response to OS Benefits
March 3rd 2016Bear discusses studies adding treatments to chemotherapy in order to increase the pathological complete response (pCR) rate and the difficulties of translating those benefits into better overall survival (OS) rates for patients with breast cancer.
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Dr. Eric P. Winer on Pathologic Complete Response and Disease Free Survival in Breast Cancer
March 1st 2016Winer says patients who do well on carboplatin and show both a good pathologic complete response and good disease free survival may be patients who have refractory disease and are responding well to the treatment, while others may be patients who were bound to do well regardless.
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Dr. Yardena Samuels on Targeting Pathways Instead of Proteins in Melanoma
March 1st 2016Yardena Samuels, PhD, on the ineffectiveness of targeting a single gene of proteins in patients with melanoma. Samuels says this strategy may work for the short term for treatment, but patients would tend to develop a resistance much quicker to treatment strategies using this method.
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Dr. Randal S. Weber on Anti-EGFR Agents Showing Efficacy in Squamous Cell Carcinoma
February 24th 2016Weber says overactivity of these EGFR receptors may cause SCC tumors to become more aggressive. He adds that in a recent, small-scale study, effectively blocking the EGFR receptor in the tumor with anti-EGFR therapy proved to be successful.
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Dr. Daniel J. Haraf on a Less Toxic Treatment for Patients With Head and Neck Cancer
February 24th 2016Haraf says historically, medical professionals have treated patients with radiation therapy "from their eyebrows to their collarbones." This approach, while effective, has resulted in an abundance of toxicities.
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Dr. Erika P. Hamilton on Difficulties of Treating Brain Metastases in Breast Cancer
February 19th 2016Hamilton says there are currently not very many "good" drugs for treating these metastases. She adds that the mainstay for treating these metastases is usually some form of radiation therapy, such as whole brain radiation.
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