Ibrutinib Plus Umbralisib Induce Survival Benefit in Patients With CLL
August 17th 2020Matthew Davids, MD, MMSc, discusses the longer-term follow-up data from the phase 3 UNITY-CLL clinical trial, which evaluated umbralisib in combination with ibrutinib as treatment of patients with chronic lymphocytic leukemia.
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Radiosurgery Improves Clinical Outcomes in Brain Metastasis Treatment
August 14th 2020Joshua Palmer, MD, discusses a pooled analysis of 2 randomized clinical trials that compared how clinical outcomes and quality of life were impacted with stereotactic radiosurgery versus whole-brain radiation therapy in patients with brain metastases.
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Roberge Explains the Role of Radiotherapy in Treatment of Brain Metastasis
August 14th 2020David Roberge, MD, discusses the current role of radiosurgery in the brain metastasis treatment paradigm, a topic he reviewed during a presentation at the 2020 Society of Neuro-Oncology Conference on Brain Metastases.
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Phase 3 Trial Investigates T-DM1 and Pertuzumab in HER2+ Breast Cancer
August 12th 2020Julie Gralow, MD, discusses the primary analysis of trastuzumab emtansine plus pertuzumab versus trastuzumab, pertuzumab, and taxane, after anthracyclines as adjuvant therapy in patients with high-risk HER2-positive early breast cancer in the of the KAITLIN study.
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NSCLC With EGFR Exon 20 Shows Benefit With Mobocertinib Over Chemotherapy
August 11th 2020Leora Horn, MD, MSc, discusses the data accrued from Flatiron and from a phase 1/2 trial of patients with refractory non–small cell lung cancer with EGFR exon 20 insertions receiving mobocertinib compared with currently approved therapies.
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Exploring Updated Data for Large B-Cell Non-Hodgkin Lymphoma
August 5th 2020Nilanjan Ghosh, MD, discusses the significance of the data from a pilot study of lisocabtagene maraleucel in patients ineligible for second-line transplant with relapsed/refractory aggressive large B-cell non-Hodgkin lymphoma.
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Treatment Landscape for Acute Myeloid Leukemia Appears Hopeful for Patients
July 31st 2020Eunice Wang, MD, discusses the excitement she has experienced in the treatment landscape of acute myeloid leukemia over the last several years due to the number of new treatment options approved by the FDA.
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