Targeted Oncology interviews feature the world's leading oncologists sharing their insights on the latest news and advances in diagnostic testing, biomarkers, pathways, immunotherapy, and targeted therapeutics for better application into clinical practice.
Examining the Impact of the FLAURA Trial in EGFR-Mutant NSCLC
March 14th 2020Zofia Piotrowska, MD, MHS, discusses the rationale for conducting the FLAURA trial in patients with <em>EGFR</em>-mutant non–small cell lung cancer and how the use of osimertinib impacted the treatment landscape for this patient population.
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Optimizing Treatment Approaches for Hepatocellular Carcinoma
March 10th 2020David J. Pinato, MD, PhD, discusses the importance of utilizing a multidisciplinary approach when treating patients with hepatocellular carcinoma and how this approach helps optimize patient outcomes now as well as how it will help in the near future as more therapies emerge.
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Questioning Future Combinations and Targets for CAR T Cell in DLBCL
February 25th 2020Lori A. Leslie, MD, discusses chimeric antigen receptor T-cell therapy as a treatment for diffuse large B-cell lymphoma and the positive results demonstrated for this agent in patients with relapsed/refractory disease.
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Nadofaragene Firadenovec Shows Durable Responses in NMIBC
February 18th 2020Stephen Boorjian, MD, discusses the efficacy results of the phase II study intravesical nadofaragene firadenovec in patients with high-grade, Bacillus Calmette-Guerin unresponsive nonmuscle invasive bladder cancer, which he presented at the 2020 Genitourinary Cancer Symposium.
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Expert Shares Rationale for GSI Plus CAR T-Cell Combination in Myeloma
February 13th 2020Andrew J. Cowan, MD, explains the rationale for a phase I clinical trial in which a gamma-secretase inhibitor was combined with CAR T-cell therapy as treatment for heavily pretreated patients with multiple myeloma.
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Evaluating the Role of CAR T-Cell Therapy in Relapsed/Refractory DLBCL
February 12th 2020Karl M. Kilgore, PhD, discusses the role of chimeric antigen receptor T-cell therapy as treatment of patients with relapsed/refractory diffuse large B-cell lymphoma and where this option might fit into the landscape in the future.
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