Key opinion leaders review clinical cases in renal cell carcinoma, focusing on recent advances, treatment options, and clinical trials impacting treatment.
EP. 1: Case 1: Metastatic Renal Cell Carcinoma, Intermediate Risk
Tom Hutson, DO, PharmD, reviews the case of a 59-year-old woman with metastatic renal cell carcinoma, with intermediate risk and the role of risk assessment in patient management.
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EP. 2: Case 1: Systemic Therapy Options in RCC
The expert panel discusses systemic therapy options recommended in NCCN Guidelines for patient with intermediate- and poor-risk mRCC.
EP. 3: Case 1: Intermediate- and Poor Risk First-Line mRCC Treatments
Renal cell carcinoma experts discuss key efficacy data for first-line immunotherapy combinations in intermediate- and poor-risk patients with mRCC.
EP. 4: Case 1: CLEAR Trial in mRCC
Tom Hutson, DO, PharmD, reviews data from phase 3 CLEAR trial that evaluates efficacy and safety of frontline lenvatinib and pembrolizumab or everolimus or sunitinib.
EP. 5: Case 1: Practical Considerations in mRCC
The expert panel discusses practical considerations when choosing first-line treatment in mRCC in light of CLEAR trial data.
EP. 6: Case 1: CheckMate 9ER mRCC Trial
Tom Hutson, DO, PharmD, discusses efficacy and data from CheckMate 9ER, a phase 3 study, and considerations in selecting this regimen.
EP. 7: Case 1: Patient Management in RCC
Renal cell carcinoma panel discusses factors impacting first-line treatment selection and patient monitoring and adverse-event management in patients with intermediate- and poor-risk mRCC.
EP. 8: Case 2: Metastatic RCC, Favorable Risk
Eric Jonasch, MD, discusses a 62-year-old man with favorable-risk metastatic RCC and goals and treatment options for such a patient.
EP. 9: Case 2: Favorable-Risk First-Line Treatments in mRCC
The expert panel and Dr Eric Jonasch discuss data on first-line immunochemotherapy combinations for favorable-risk mRCC.
EP. 10: Case 2: Second-Line Treatments in Favorable-Risk mRCC
Eric Jonasch, MD, and the panel discuss NCCN Guidelines’ preferred second-line treatment options in mRCC.
EP. 11: Case 2: Adverse-Event Management in Favorable-Risk RCC
RCC experts discuss dose modifications and management of adverse events in patients with favorable-risk mRCC.
EP. 12: Case 2: TIVO-3 Study in mRCC
Dr Eric Jonasch and the panel discuss TIVO-3 trial data and use of tivozanib and HIF3α inhibitors in mRCC.
EP. 13: Case 3: A New Horizon in Adjuvant Therapy for RCC
Bradley McGregor, MD, reviews the case of a 62-year-old man with mRCC and the use of adjuvant therapy for RCC.
EP. 14: Case 3: Multidisciplinary Team Engagement in RCC
The expert panel discusses the role of multidisciplinary teams in treatment of patients with RCC.
EP. 15: Case 3: mRCC Keynote-564 Study
Bradley McGregor, MD, reviews data from the Keynote-564 study on the use of immunotherapy in the adjuvant setting.
EP. 16: Case 3: Keynote-564 Discussion and Adjuvant Treatment in mRCC
The expert panel discusses trials underway in the adjuvant setting and the role of adjuvant therapy in patients with RCC.